Brand perception is shaped not only by product attributes but also by cultural frameworks that determine how consumers interpret symbols, values, imagery, and brand narratives. Cultural frames act as cognitive filters influencing meaning-making, emotional resonance, trust, identity, and purchasing decisions. This research synthesizes theories from cultural psychology, semiotics, and global marketing to explore how cultural lenses shape brand perception across diverse markets. The proposed Cultural Frame–Brand Interpretation Model (CF-BIM) demonstrates how localized cultural values, belief systems, language structures, and social norms mediate brand meaning. The study concludes with implications for multinational branding strategies, digital localization, ethnographic marketing, and cross-cultural segmentation.